\u677e\u4e95\u3000\u6bc5\u3001\u9678\u4e0a\u810a\u690e\u52d5\u7269\u76ae\u819a\u306e\u9069\u5fdc\u9032\u5316\u6a5f\u69cb\u3001JT\u751f\u547d\u8a8c\u992820\u5468\u5e74\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u30b7\u30ea\u30fc\u30ba\u3010\u7b2c3\u30014\u5408\u540c\u3011\uff5e\u7cfb\u7d71\u95a2\u4fc2\u3001\u5f62\u614b\u3001\u751f\u614b\u3092\u3080\u3059\u3076\u65b0\u30b2\u30ce\u30e0\u6642\u4ee3\u306e\u9032\u5316\u5b66\uff5e\u30012014\u5e744\u670826\u65e5\u3001JT\u751f\u547d\u8a8c\u9928\uff08\u9ad8\u69fb\u5e02\u30fb\u5927\u962a\u5e9c\uff09<\/a><\/p>\n\n\n\n<\/p>\n\n\n\n
\u677e\u4e95\u3000\u6bc5\u3001\u76ae\u819a\u7279\u7570\u7684\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u578b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bcSASPase\u306e\u7372\u5f97\u3068\u54fa\u4e73\u985e\u76ae\u819a\u8868\u76ae\u6a5f\u80fd\u306e\u9032\u5316\u3001\u65e5\u672c\u907a\u4f1d\u5b66\u4f1a\u7b2c85\u56de\u5927\u4f1a\u30012013\u5e749\u670819\u65e5\u3001\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u65e5\u5409\u30ad\u30e3\u30f3\u30d1\u30b9\uff08\u6a2a\u6d5c\u5e02\u30fb\u795e\u5948\u5ddd\u770c\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\u3001\u76ae\u819a\u7279\u7570\u7684\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u578b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bcSASPase\u306e\u7372\u5f97\u3068\u54fa\u4e73\u985e\u76ae\u819a\u8868\u76ae\u6a5f\u80fd\u306e\u9032\u5316\u3001\u56fd\u7acb\u907a\u4f1d\u5b66\u7814\u7a76\u6240\u7814\u7a76\u96c6\u4f1a\u3000\u65b0\u6a5f\u80fd\u7372\u5f97\u306e\u5206\u5b50\u9032\u5316\u30012013\u5e748\u670818\u65e5\u3001\u56fd\u7acb\u907a\u4f1d\u5b66\u7814\u7a76\u6240\uff08\u4e09\u5cf6\u5e02\u30fb\u9759\u5ca1\u770c\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\u3001\u76ae\u819a\u7279\u7570\u7684\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u578b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bcSASPase\u3068\u54fa\u4e73\u985e\u76ae\u819a\u8868\u76ae\u306e\u9032\u5316\u3001\u7b2c18\u56de\u65e5\u672c\u75c5\u614b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30012013\u5e748\u670817\u65e5\u3001\u5343\u91cc\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u30bb\u30f3\u30bf\u30fc\uff08\u8c4a\u4e2d\u5e02\u30fb\u5927\u962a\u5e9c\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\u3001\u54fa\u4e73\u985e\u76ae\u819a\u8868\u76ae\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u91cf\u3092\u5236\u5fa1\u3059\u308b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u3068\u76ae\u819a\u8868\u76ae\u306e\u9032\u5316\u3001\u7b2c1\u56de\u30e1\u30c7\u30a3\u30b7\u30e7\u30ca\u30eb\u30ca\u30ce\u30c6\u30af\u7814\u7a76\u4f1a\u30012013\u5e746\u670828\u65e5\u3001\u30ad\u30e3\u30f3\u30d1\u30b9\u30d7\u30e9\u30b6\u4eac\u90fd\uff08\u4eac\u90fd\u5e02\u30fb\u4eac\u90fd\u5e9c\uff09<\/p>\n\n\n\n
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Matsui T: Mammalian Skin-specific Retroviral-like Aspartic Protease, SASPase is a Key Modulator of Skin Moisturization and Evolution, Integration of Cell Biology and Materials. RSC-iCeMS Joint International Symposium Cell-Material Integrationand Biomaterial Sciences 2013\u5e743\u670818\u65e5\u3001\u4eac\u90fd\u5927\u5b66iCeMS\uff08\u4eac\u90fd\u5e02\u30fb\u4eac\u90fd\u5e9c\uff09<\/p>\n\n\n\n
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Matsui T: Mammalian Skin-specific Retroviral-like Aspartic Protease, SASPase is a Key Modulator of Skin Moisturization and Evolution \u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7 \u767a\u751f\u3068\u9032\u5316\u306b\u95a2\u308f\u308b\u30c8\u30e9\u30f3\u30b9\u30dd\u30be\u30f3\u7531\u6765\u306eDNA \u3000\u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u3000 2012\u5e7412\u670810\u65e5\u3000\uff08\u798f\u5ca1\u5e02\u30fb\u798f\u5ca1\u770c\uff09<\/p>\n\n\n\n
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Matsui T: Mammalian Skin-specific Retroviral-like Aspartic Protease, SASPase is a Key Modulator of Skin Moisturization FUJIHARA SEMINAR 2012, A new horizon of retroposon research\u30002012\u5e748\u67083\u65e5\u3000\uff08\u4eac\u90fd\u5e02\u30fb\u4eac\u90fd\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\u3001\u3000\u810a\u690e\u52d5\u7269\u9678\u4e0a\u9032\u51fa\u306e\u8b0e\u3068\u76ae\u819a\u306e\u7f8e\u5bb9\u3000\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300c\u30bf\u30a4\u30c8\u30b8\u30e3\u30f3\u30af\u30b7\u30e7\u30f3\u306e\u4ed5\u7d44\u307f\u300d\u3000\u7b2c 29 \u56de\u65e5\u672c\u7f8e\u5bb9\u76ae\u819a\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30002011\u5e749\u670810\u65e5\u3000\uff08\u4e0b\u95a2\u5e02\u30fb\u5c71\u53e3\u770c\uff09<\/p>\n\n\n\n
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\u3010\u30bb\u30df\u30ca\u30fc \/ Seminar\u3011<\/h2>\n\n\n\n
Takeshi Matsui: Molecular Mechanism of Corneoptosis, keratinocyte-specific cell death during the formation of the epidermal barrier, Institute of Biotechnology and Molecular Biology, Adam Mickiewicz University, Pozna\u0144, Poland (Hosted by Dr. Micha\u0142 Gdula), 8th, Sep 2025<\/p>\n\n\n\n
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\u677e\u4e95\u6bc5\uff1a\u5206\u96e2\u9846\u7c92\u5c64\u7d30\u80de\u3092\u7528\u3044\u305f\u8868\u76ae\u89d2\u8cea\u5c64\u30d0\u30ea\u30a2\u306e\u5f62\u6210\u6a5f\u69cb\u89e3\u6790 Dissecting the formation of the stratum corneum by isolated stratum granulosum cells. \u5317\u6d77\u9053\u5927\u5b66\u76ae\u819a\u79d1\u3000\u7279\u5225\u8b1b\u6f14 2016\u5e747\u670813\u65e5\uff08\u5317\u6d77\u9053\u30fb\u672d\u5e4c\u5e02\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u6bc5\uff1a\u5206\u96e2\u9846\u7c92\u5c64\u7d30\u80de\u3092\u7528\u3044\u305f\u76ae\u819a\u8868\u76ae\u89d2\u5c64\u30d0\u30ea\u30a2\u5f62\u6210\u6a5f\u69cb\u306e\u89e3\u6790. \u6771\u4eac\u8fb2\u696d\u5de5\u696d\u5927\u5b66\u5de5\u5b66\u90e8\u6709\u6a5f\u6750\u6599\u5316\u5b66\u79d1\u6750\u6599\u5065\u5eb7\u79d1\u5b66\u5bc4\u9644\u8b1b\u5ea7\u30bb\u30df\u30ca\u30fc 2016\u5e746\u670830\u65e5\uff08\u6771\u4eac\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u6bc5\uff1a\u5206\u96e2\u9846\u7c92\u5c64\u7d30\u80de\u3092\u7528\u3044\u305f\u76ae\u819a\u8868\u76ae\u89d2\u8cea\u30d0\u30ea\u30a2\u5f62\u6210\u6a5f\u69cb\u306e\u89e3\u6790. \u81ea\u7136\u79d1\u5b66\u7814\u7a76\u6a5f\u69cb\u751f\u7406\u5b66\u7814\u7a76\u6240 \u90e8\u9580\u516c\u958b\u30bb\u30df\u30ca\u30fc. 2016\u5e746\u670824\u65e5\uff08\u611b\u77e5\u770c\u30fb\u5ca1\u5d0e\u5e02\uff09<\/p>\n\n\n\n
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\u3010\u53e3\u982d\u767a\u8868 \/ Oral Presentations\u3011<\/h2>\n\n\n\n
Takeshi Matsui, Shota Kawanami, Keiichiro Shiraga, Yuichi Ogawa, Masayuki Amagai: Elevation of Intracellular Bulk Water Content Coincides with Calcium Ion Influx during Corneoptosis in Stratum Granulosum Cells, 54th ESDR annual meeting-Concurrent Session, 11th, Sep, 2025, Antwerp, Bergium<\/p>\n\n\n\n
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Takeshi Matsui, Shota Kawanami, Keiichiro Shiraga, Yuichi Ogawa, Masayuki Amagai: Elevation of Intracellular Bulk Water Content Coincides with Calcium Ion Influx during Corneoptosis in Stratum Granulosum Cells, 54th ESDR annual meeting-E2BRN, 10th, Sep, 2025, Antwerp, Bergium<\/p>\n\n\n\n
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Takeshi Matsui, AI Hirabayashi, Mayuko Sato, Kiminori Toyooka, Hiroyuki Sasaki, Masayuki Amagai: Three distinct ultrastructural stages of dying epidermal stratum granulosum cells during corneoptosis revealed by high-pressure freezing, 49th JSID annual meeting, 8th, Dec, 2024, Nagoya, Japan
(Selected as Oral Presentation in Concurrent Session)<\/p>\n\n\n\n
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Takeshi Matsui: A unique mode of functional cell death in stratum granulosum cells, corneoptosis, Concurrent Session, Epidermal Structure and Function, 50th Annual ESDR Meeting-Virtual, Sep 23, 2021\uff08ONLINE\uff09
(Selected as Oral Presentation in Concurrent Session)<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\uff1a\u76ae\u819a\u8868\u76ae\u9846\u7c92\u5c64\u7d30\u80de\u304c\u8d77\u3053\u3059\u7d30\u80de\u6b7b\u306b\u304a\u3051\u308b\u3001\u7d30\u80de\u5185\u9178\u6027\u5316\u3068\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u578b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u306e\u6d3b\u6027\u5316\u3001\u7b2c23\u56de\u65e5\u672c\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u7814\u7a76\u4f1a\u3000\u590f\u671f\u30bb\u30df\u30ca\u30fc\u30002021\u5e747\u67081\u65e5\uff08\u30aa\u30f3\u30e9\u30a4\u30f3\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\uff1a\u76ae\u819a\u8868\u76ae\u89d2\u5316\u6642\u306e\u9846\u7c92\u5c64\u7d30\u80de\u304c\u8d77\u3053\u3059\u7d30\u80de\u6b7b\uff08\u30b3\u30eb\u30cd\u30aa\u30c8\u30fc\u30b7\u30b9\uff09\u306b\u306f\u7d30\u80de\u5185\u9178\u6027\u5316\u304c\u5fc5\u8981\u3067\u3042\u308b\u3001\u65e5\u672c\u7d30\u80de\u751f\u7269\u5b66\u4f1a\u3000\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d714\u3000\u7d30\u80de\u5897\u6b96\u30fb\u7d30\u80de\u5206\u5316\u30fb\u7d30\u80de\u6b7b 2021\u5e747\u67081\u65e5\uff08\u30aa\u30f3\u30e9\u30a4\u30f3\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\u3001\u81fc\u4e95\u3000\u666f\u5b50\u3001\u845b\u91ce\u3000\u83dc\u3005\u5b50\u3001\u53e4\u5e02\u3000\u7950\u6a39\u3001\u5e73\u6797\u3000\u611b\u3001\u5929\u8c37\u3000\u96c5\u884c\uff1a\u76ae\u819a\u8868\u76ae\u9846\u7c92\u5c64\u7d30\u80de\u52d5\u614b\u304b\u3089\u660e\u3089\u304b\u306b\u3059\u308b\u9678\u4e0a\u810a\u690e\u52d5\u7269\u306e\u6c17\u76f8\u74b0\u5883\u3078\u306e\u9069\u5fdc\u9032\u5316\u6a5f\u69cb\u3001\u7b2c39\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u9032\u5316\u7d30\u80de\u751f\u7269\u5b66\uff1a\u7d30\u80de\u52d5\u614b\u306e\u5909\u5316\u306f\u3069\u306e\u3088\u3046\u306b\u9032\u5316\u3092\u99c6\u52d5\u3059\u308b\u304b2016\u5e7412\u67081\u65e5\u30d1\u30b7\u30d5\u30a3\u30b3\u6a2a\u6d5c\uff08\u6a2a\u6d5c\u5e02\u30fb\u795e\u5948\u5ddd\u770c\uff09(Selected as an Oral Presentation)<\/p>\n\n\n\n
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Matsui T and Amagai M: Initiation of cornification is regulated by Ca2+<\/sup> and pH in isolated mouse stratum granulosum cells. \u7b2c68\u56de\u65e5\u672c\u7d30\u80de\u751f\u7269\u5b66\u4f1a\u5927\u4f1a 2016\u5e746\u670815\u65e5\uff08\u4eac\u90fd\u5e02\u3001\u4eac\u90fd\u5e9c\uff09<\/p>\n\n\n\n<\/p>\n\n\n\n
Matsui T, Furuichi Y, Hirabayashi A and Amagai M: Initiation of cornification is regulated by Ca2+<\/sup> and pH in isolated mouse stratum granulosum cells. \u65e5\u672c\u7814\u7a76\u76ae\u819a\u79d1\u5b66\u4f1a \u7b2c40\u56de\u5e74\u6b21\u5b66\u8853\u5927\u4f1a, Dec 12th, 2015, Okayama, Japan.(Selected as the Concurrent Session)<\/p>\n\n\n\n<\/p>\n\n\n\n
Matsui T, Hirabayashi A, Sato M, Toyooka K, Amagai M: Initiation of cornification is regulated by Ca2+<\/sup> and pH in isolated mouse stratum granulosum cells. European Society for Dermatology,2015\u5e749\u670810\u65e5(Rotterdam, Holand)<\/p>\n\n\n\n<\/p>\n\n\n\n
Matsui T, Miyamoto K, Kubo A, Kawasaki H, Ebihara T, Hata K, Ichinose S, Imoto I, Inazawa J, Kudoh J, Amagai M: Mammalian Skin-specific Retroviral-like Aspartic Protease, SASPase is a Key Modulator of Skin Moisturization. Joint Meeting of the 45th Annual Meeting of the Japanese Society of Developmental Biologists & the 64th Annual Meeting of the Japan Society for Cell Biology 2012\u5e745\u670829\u65e5\uff08\u795e\u6238\u5e02\u30fb\u5175\u5eab\u770c\uff09(Selected as an Oral Presentation)<\/p>\n\n\n\n
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Matsui T: Endogenous Retroviral-like Aspartic Protease, SASPase as a key modulator of skin moisturization. The 8th Okazaki Biology Conference (OBC8) Speciation and Adaptation II – Environment and Epigenetics – 2012\u5e743\u670823\u65e5\uff08\u5ca1\u5d0e\u5e02\u30fb\u611b\u77e5\u770c\uff09(Selected as a Short Presentation)<\/p>\n\n\n\n
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Matsui T,Miyamoto K, Kubo A, Kawasaki H, Ebihara T, Hata K, Ichinose S, Imoto I, Inazawa J, Kudoh J, Amagai M: SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing. \u65e5\u672c\u7814\u7a76\u76ae\u819a\u79d1\u5b66\u4f1a \u7b2c36\u56de\u5e74\u6b21\u5b66\u8853\u5927\u4f1a Plenary 2011\u5e7412\u670810\u65e5\uff08\u4eac\u90fd\u5e02\u30fb\u4eac\u90fd\u5e9c\uff09(Selected as the Plenary Session)<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\u3001\u5bae\u672c\u3000\u61b2\u4e00\u3001\u4e45\u4fdd\u3000\u4eae\u6cbb\u3001\u5ddd\u5d0e\u3000\u6d0b\u3001\u6d77\u8001\u539f\u3000\u5168\u3001\u7551\u3000\u548c\u4e5f\u3001\u5e02\u91ce\u702c\u3000\u5fd7\u6d25\u5b50\u3001\u4e95\u672c\u3000\u9038\u52e2\u3001\u7a32\u6fa4\u3000\u8b72\u6cbb\u3001\u5de5\u85e4\u3000\u7d14\u3001\u5929\u8c37\u3000\u96c5\u884c:\u76ae\u819a\u8868\u76ae\u9846\u7c92\u5c64\u7279\u7570\u7684\u306a\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u578b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bcSASPase\u306f\u3001Profilaggrin\u304b\u3089Filaggrin\u306e\u5206\u89e3\u3092\u5236\u5fa1\u3057\u3001\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u91cf\u3092\u8abf\u7bc0\u3059\u308b\u30022011\u5e749\u670822\u65e5\u3000\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u3000\uff08\u4eac\u90fd\u5e02\u30fb\u4eac\u90fd\u5e9c\uff09<\/p>\n\n\n\n
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\u677e\u4e95\u3000\u6bc5\u3001\u5bae\u672c\u3000\u61b2\u4e00\u3001\u4e45\u4fdd\u3000\u4eae\u6cbb\u3001\u5ddd\u5d0e\u3000\u6d0b\u3001\u6d77\u8001\u539f\u3000\u5168\u3001\u7551\u3000\u548c\u4e5f\u3001\u5e02\u91ce\u702c\u3000\u5fd7\u6d25\u5b50\u3001\u4e95\u672c\u3000\u9038\u52e2\u3001\u7a32\u6fa4\u3000\u8b72\u6cbb\u3001\u5de5\u85e4\u3000\u7d14\u3001\u5929\u8c37\u3000\u96c5\u884c: \u9678\u4e0a\u810a\u690e\u52d5\u7269\u306b\u304a\u3044\u3066\u7372\u5f97\u3055\u308c\u305f\u76ae\u819a\u8868\u76ae\u9846\u7c92\u5c64\u7279\u7570\u7684\u306a\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u578b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bcSASPase\u306f\u3001\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u91cf\u3092\u8abf\u7bc0\u3059\u308b\u3002\u65e5\u672c\u9032\u5316\u5b66\u4f1a\u30002011\u5e747\u670830\u65e5\uff08\u4eac\u90fd\u5e02\u30fb\u4eac\u90fd\u5e9c\uff09<\/p>\n\n\n\n
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\u3010\u53e3\u982d\u767a\u8868\uff08\u5171\u8457\u8005\uff09 \/ Oral Presentations (Coauthor)\u3011<\/h2>\n\n\n\n
\u4f50\u85e4\u4e03\u7dd2\u3001\u591a\u7530\u660e\u5f18\u3001\u677e\u4e95\u3000\u6bc5\uff1a\u672a\u5229\u7528\u8cc7\u6e90\u30e6\u30ba\u3055\u306e\u3046\u30a8\u30ad\u30b9\u306f\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u306e\u7d30\u80de\u5185 Ca2+<\/sup>\u6fc3\u5ea6\u4e0a\u6607\u3092\u4fc3\u3059\u3001\u7b2c3\u56de\u65e5\u672c\u5316\u7ca7\u54c1\u6280\u8853\u8005\u4f1a\u5b66\u8853\u96c6\u4f1a\u3001\u53e3\u982d\u767a\u8868\u3001\u30d1\u30b7\u30d5\u30a3\u30b3\u6a2a\u6d5c\uff08\u795e\u5948\u5ddd\u770c\u6a2a\u6d5c\u5e02\uff092025\u5e7412\u670810\u65e5<\/p>\n\n\n\n\u4f50\u85e4\u4e03\u7dd2\u3001\u591a\u7530\u660e\u5f18\u3001\u677e\u4e95\u6bc5\uff1a\u672a\u5229\u7528\u8cc7\u6e90\u30e6\u30ba\u3055\u306e\u3046\u30a8\u30ad\u30b9\u306f\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u7d30\u80de\u5185Ca\u00b2\u207a\u6fc3\u5ea6\u4e0a\u6607\u3092\u4fc3\u3059\u3001Citrus Junos Fruit Extracts Increase Intracellular Ca2+<\/sup> Levels in Human Keratinocytes\u3001\u7b2c50\u56de\u65e5\u672c\u9999\u7ca7\u54c1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u3001\u53e3\u982d\u767a\u8868\u3001\u6709\u697d\u753a\u671d\u65e5\u30db\u30fc\u30eb\uff08\u6771\u4eac\u90fd\uff092025\u5e747\u67084\u65e5<\/p>\n\n\n\nShota Kawanami, Keiichiro Shiraga, Yuichi Ogawa, Keitaro Fukuda, Masayuki Amagai, Takeshi Matsui: Linking intracellular bulk water increase to elevated calcium levels during corneoptosis in stratum granulosum cells. Plenary session III, 49th JSID annual meeting, 8th, Dec, 2024, Nagoya, Japan
(Selected as Oral Presentation in Plenary Session)<\/p>\n\n\n\n
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\u5927\u6e2f\u5b9f\u67da\u3001\u51fa\u5ddd \u670b\u7f8e\u3001\u591a\u7530 \u660e\u5f18\u3001\u677e\u4e95 \u6bc5: \u672a\u5229\u7528\u8cc7\u6e90\u3067\u3042\u308b\u3086\u305a\u306e\u643e\u6c41\u30ab\u30b9\u304b\u3089\u62bd\u51fa\u3057\u305f\u30a8\u30ad\u30b9\u306f\u30d2\u30c8\u89d2\u5c64\u306e\u5265\u96e2\u4fc3\u9032\u306b\u95a2\u308f\u308b\u3001\u7b2c2\u56de\u65e5\u672c\u5316\u7ca7\u54c1\u6280\u8853\u8005\u4f1a\u5b66\u8853\u5927\u4f1a\u30012024\u5e7411\u670820\u65e5\u3001\u795e\u6238\u56fd\u969b\u4f1a\u8b70\u5834<\/p>\n\n\n\n
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Ruebsam M, Bhosale A, Tellkamp F, Matsui T, Amagai M, Kr\u00fcger M, Niessen CM: <\/strong>Actin dependent regulation of epidermal differentiation and barrier formation.
ISID 2023, Concurrent Mini-Symposium, Tokyo, May 13th, 2023.<\/p>\n\n\n\n<\/p>\n\n\n\n
Fukuda <\/sup>K, Ito <\/sup>Y, Furuichi Y, Miyano T, Tanaka RJ, Matsui T, Amagai M: Stratum corneum homeostasis requires three-stepwise pH zones mediated by the functional cell death of keratinocytes, corneoptosis.
ISID 2023, Select ePoster Discussions, Tokyo, May 12th, 2023.<\/p>\n\n\n\n<\/p>\n\n\n\n
\u8c4a\u5ca1\u3000\u516c\u5fb3\u3001\u677e\u4e95\u3000\u6bc5\u3001\u8a31\u6590\u3000\u9ebb\u7f8e\u3001\u661f\u91ce\u3000\u5409\u5ef6: MirrorCLEM\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\u3068\u52d5\u690d\u7269\u8a66\u6599\u3078\u306e\u5fdc\u7528\u3002\u65e5\u672c\u9855\u5fae\u93e1\u5b66\u4f1a\u7b2c75\u56de\u5b66\u8853\u8b1b\u6f14\u4f1a 2019\u5e746\u670817\u65e5\uff08\u540d\u53e4\u5c4b\u5e02\u3001\u611b\u77e5\u770c\uff09<\/p>\n\n\n\n
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\u5409\u539f\u3000\u771f\u8863\u3001\u524d\u7530\u3000\u8e8d\u3001\u5ddd\u5143\u3000\u5bdb\u7ae0\u3001\u5742\u4e0a\u3000\u4e07\u91cc\u3001\u8a31\u6590\u3000\u9ebb\u7f8e\u3001\u81fc\u4e95\u3000\u666f\u5b50\u3001\u845b\u91ce\u3000\u83dc\u3005\u5b50\u3001\u677e\u4e95\u3000\u6bc5\u3001\u8c4a\u5ca1\u3000\u516c\u5fb3\uff1a\u5149-\u96fb\u5b50\u76f8\u95a2\u9855\u5fae\u93e1\u30b7\u30b9\u30c6\u30e0\u3092\u7528\u3044\u305f\u57f9\u990a\u7d30\u80de\u306e\u89b3\u5bdf\u3002\u65e5\u672c\u9855\u5fae\u93e1\u5b66\u4f1a\u7b2c75\u56de\u5b66\u8853\u8b1b\u6f14\u4f1a 2019\u5e746\u670817\u65e5\uff08\u540d\u53e4\u5c4b\u5e02\u3001\u611b\u77e5\u770c\uff09<\/p>\n\n\n\n
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Furuichi Y, Matsui T, Kawasaki H,Shiohama A, Sasaki T, Furuse M, Amagai M: Intrinsic homeostatic mechanism of stratum corneum regulated by pH. IID 2018 International Investigative Dermatology. May 19, 2018 (Portland, USA)<\/p>\n\n\n\n
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Suzuki Y, MatsuiT, Yamanoi Y, AtsugiT, KuboA, AmagaiM, Tominaga M: Functional expression of TRPV3 in the superficial layer of stratum granulosum of mouse epidermis. The 94th Annual Meeting of the Physiological Society of Japan March 29, 2017\uff08Hamamatsu, Japan\uff09<\/p>\n\n\n\n
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Usui K, Matsui T, Furuichi Y, Kadono N, Hirabayashi A, Mayuko S, Toyooka K, Amagai M: Visualization of in vivo keratin networks in mouse stratum granulosum reveals dynamic cytoskeletal changes during cornification. The 42nd Japanese Society for Investigative Dermatology. Dec 16, 2017\uff08Kochi, Japan\uff09(Selected as Plenary Session Talk)<\/p>\n\n\n\n
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Furuichi Y, Matsui T, Amagai M: zwReal time 3D in vivo pH imaging of stratum corneum reveals complex morphology-based regulation in mice. (Selected as concurrent oral session) The 76th Annual meeting of for Investigative Dermatology. April 28, 2017 (Portland, USA\uff09<\/p>\n\n\n\n
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\u53e4\u5e02\u3000\u7950\u6a39\uff0c\u677e\u4e95\u3000\u6bc5\uff0c\u5929\u8c37\u3000\u96c5\u884c\uff1a 3D in vivo pH \u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u306b\u3088\u308a\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u30de\u30a6\u30b9\u89d2\u8cea\u5c64 pH \u306e\u69cb\u9020\u7684\u5236\u5fa1\u6a5f\u69cb\u3002\u7b2c24\u56de\u5206\u5b50\u76ae\u819a\u30d5\u30a9\u30fc\u30e9\u30e0\u30002017\u5e744\u670814\u65e5\uff08\u6771\u4eac\uff09<\/p>\n\n\n\n
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Matsui T: Initiation of cornification is regulated by Ca2+ and pH in isolated mouse stratum granulosum cells.27th CDB Meeting \u201cBody Surface Tactics: Cellular crosstalk for the generation of super-biointerfaces\u201d Sep 9, 2016\uff08Kobe, Japan\uff09<\/p>\n\n\n\n
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Furuichi Y, Matsui T, Amagai M: Real time 3D in vivo pH imaging of stratum corneum revealed complex morphology-based regulation in mice. The 41th Japanese Society for Investigative Dermatology. Dec 10, 2016 \uff08Sendai, Japan\uff09
(Selected as Plenary Session Talk)<\/p>\n\n\n\n
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\u3010\u30dd\u30b9\u30bf\u30fc\u767a\u8868\uff08\u5171\u8457\u8005\uff09 \/ Poster Presentations (Coauthor)\u3011<\/h2>\n\n\n\n
Kuga Kobayashi, Chihaya Asakura, Takeshi Matsui:Optogenetically Controlled Intracellular Ca\u00b2\u207a Elevation Induces Differentiation of Primary Cultured Mouse Keratinocytes.50th<\/sup> Annual Meeting of the Japanese Society for Investigative Dermatology, Poster, Kofu, Yamanashi, 5th<\/sup>-7th<\/sup>, Dec, 2025.<\/p>\n\n\n\nNao Satoh, Tada, Takeshi Matsui: Citrus Junos Fruit Extracts Elevate Intracellular Ca2+ Levels via TRPV4 in Human Keratinocytes50th<\/sup>Annual Meeting of the Japanese Society for Investigative Dermatology, Poster, Kofu, Yamanashi, 5th<\/sup>-7th<\/sup>, Dec, 2025.<\/p>\n\n\n\n\u7247\u6850 \u5468\u4f5c\u3001\u8352\u6728 \u4f51\u4e00\u3001\u677e\u4e95 \u6bc5\uff1a\u30d2\u30c8\u76ae\u819a\u8868\u76ae\u9846\u7c92\u5c64\u7279\u7570\u7684\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u63a2\u7d22\u3001\u7b2c48\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u3001\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3001\u30d1\u30b7\u30d5\u30a3\u30b3\u6a2a\u6d5c\uff08\u795e\u5948\u5ddd\u770c\u6a2a\u6d5c\u5e02\uff092025\u5e7412\u67084\u65e5<\/p>\n\n\n\n
Kuga Kobayashi, Chihaya Asakura, Takeshi Matsui\uff1aInduction of Keratinocyte Differentiation by Optogenetically Controlled Intracellular Ca2+<\/sup> Elevation\u3001\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3001\u7b2c77\u56de\u65e5\u672c\u7d30\u80de\u751f\u7269\u5b66\u4f1a-\u7b2c58\u56de\u65e5\u672c\u767a\u751f\u751f\u7269\u5b66\u4f1a\u5408\u540c\u5927\u4f1a\u3001\u30a6\u30a4\u30f3\u30af\u611b\u77e5\uff08\u611b\u77e5\u770c\u540d\u53e4\u5c4b\u5e02\uff09\u30012025\u5e747\u670816\u65e5<\/p>\n\n\n\nNao Sato, Akihiro Tada, Takeshi Matsui\uff1aCitrus Junos<\/em> Fruit Extracts Increase Intracellular Ca2+<\/sup> Levels in Human Keratinocytes\u3001\u7b2c77\u56de\u65e5\u672c\u7d30\u80de\u751f\u7269\u5b66\u4f1a-\u7b2c58\u56de\u65e5\u672c\u767a\u751f\u751f\u7269\u5b66\u4f1a\u5408\u540c\u5927\u4f1a\u3001\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3001\u30a6\u30a4\u30f3\u30af\u611b\u77e5\uff08\u611b\u77e5\u770c\u540d\u53e4\u5c4b\u5e02\uff09\u30012025\u5e747\u670816\u65e5<\/p>\n\n\n\n\u671d\u5009\u77e5\u98af, \u677e\u4e95\u6bc5, \u521d\u4ee3\u57f9\u990a\u8868\u76ae\u7d30\u80de\u306b\u304a\u3051\u308b\u5149\u907a\u4f1d\u5b66\u7684\u624b\u6cd5\u3092\u7528\u3044\u305f\u7d30\u80de\u5185Ca2+<\/sup>\u4e0a\u6607\u8a98\u5c0e\u7cfb\u306e\u78ba\u7acb\u3001\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u3001\u7b2c47\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u300111\u670828\u65e5\u3001\u535a\u591a<\/p>\n\n\n\n\u9b5a\u53d6\u98a8\u7f8e\u9999\u3001\u559c\u4f4f\u6587\u679d\u3001\u677e\u4e95\u6bc5\uff1a\u30d2\u30c8\u4e09\u6b21\u5143\u76ae\u819a\u30e2\u30c7\u30eb\u9846\u7c92\u5c64\u306b\u304a\u3051\u308b\u5c64\u677f\u9846\u7c92\u306e\u30e9\u30a4\u30d6\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u89e3\u6790\u3001\u7b2c46\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u30012023\u5e7412\u67087\u65e5\u3001\u795e\u6238\u30dd\u30fc\u30c8\u30a2\u30a4\u30e9\u30f3\u30c9\u3001\u795e\u6238
Live Imaging Analysis of Lamellar Granules in the Stratum Granulosum Layer of a Human Skin Equivalent Model<\/p>\n\n\n\n
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Promoter Analysis of Epidermal Stratum Granulosum-specific-transcription involved in the Cornification of Mammalian Skin<\/p>\n\n\n\n
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Tahara U, Matsui T, Atsugi T, Fukuda K, Kubo A, Amagai M: Unexpected expression of hemoglobin \u03b1 as an endogenous antioxidant in epidermal keratinocytes.
51st<\/sup> Annual Meeting of European Society for Dermatological Research 2022<\/strong>, Amsterdam, Sep 22th, 2022<\/p>\n\n\n\n<\/p>\n\n\n\n
Matsui T, Kadono-Maekubo N, Suzuki Y, Furuichi Y, Shiraga K, Sasaki H, Ishida A, Takahashi S, Okada T, Toyooka K, Sharif J, Abe T, Kiyonari H, Tominaga, M, Miyawaki A, Amagai M: A unique mode of functional cell death in stratum granulosum cells, corneoptosis.
The 51st<\/sup> NIPS International Symposium, Frontiers in Epithelial Cell Biology<\/strong>, Dec 6-8, 2021. \uff08ONLINE\uff09<\/p>\n\n\n\n<\/p>\n\n\n\n
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Matsui T: Dissecting the formation, structure and barrier function of the stratum corneum as a niche for skin microbes
The 8t<\/sup>h<\/sup> Global Network Forum on Infection and Immunity.<\/strong> \u5343\u8449\u5927\u5b66\u30012020\u5e741\u670810\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"\u3010\u62db\u5f85\u8b1b\u6f14 \/ Invited Talks\u3011 \u677e\u4e95\u3000\u6bc5\uff1a\u76ae\u819a\u3068\u306f\u3001\u4e00\u822c\u793e\u56e3\u6cd5\u4eba\u30d3\u30e5\u30fc\u30c6\u30a3\u30fc\u30b5\u30a4\u30a8\u30f3\u30b9\u30a2\u30ab\u30c7\u30df\u30fc\uff08JECA\uff09\u7b2c\u4e8c\u56de\u7dcf\u4f1a\u3000\u7279\u5225\u8a18\u5ff5\u8b1b\u6f14\u3001\u30ad\u30e3\u30f3\u30d1\u30b9\u30d7\u30e9\u30b6\u4eac\u90fd\uff08\u4eac\u90fd\u5e02\u4eac\u90fd\u5e9c\uff09\u30012026\u5e743\u670814\u65e5https:\/ …<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-56","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/56","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=56"}],"version-history":[{"count":80,"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/56\/revisions"}],"predecessor-version":[{"id":1100,"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/56\/revisions\/1100"}],"wp:attachment":[{"href":"https:\/\/takeshi-matsui-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=56"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}